⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139865 | 0.69 | — | — | |
| SCHEMBL9640525 | 0.67 | — | — | |
| SCHEMBL17501260 | 0.67 | — | — | |
| SCHEMBL7090604 | 0.63 | — | — | |
| SCHEMBL25453246 | 0.63 | — | — | |
| SCHEMBL2777129 | 0.61 | — | — | |
| SCHEMBL3054233 | 0.59 | — | — | |
| Allylamine SCHEMBL8027697 | 0.59 | — | — | |
| Sulfurous Acid SCHEMBL25287274 | 0.57 | — | — | |
| SCHEMBL175147 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233794-A1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ADT Pharmaceuticals, Inc. (US) | 2017-10-25 | — | — | EP | claimed |
| WO-2016100542-A1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ADT PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | claimed |
| EP-1509530-B1 | 2-THIA-DIBENZOAZULENES AS INHIBITORS OF TUMOUR NECROSIS FACTOR PRODUCTION AND INTERMEDIATES FOR THE PREPARATION THEREOF | PLIVA ISTRAZIVACKI INST D O O (HR) | 2006-03-15 | — | — | EP | claimed |
| US-20050182126-A1 | 2-Thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof | PILVA-ISTRAZIVACKI INSTITUT D.O.O. | 2005-08-18 | — | — | US | claimed |
| US-20050131056-A1 | 2- thia-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2005-06-16 | — | — | US | claimed |
| US-4559346-A | Certain N-octahydro-indolizinebenzamides and their use in treating psychosis, cardiac arrhythmia and hypertension | BEECHAM GROUP P.L.C. (GB) | 1985-12-17 | — | — | US | claimed |
| US-20230406803-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Kinesid Therapeutics, Inc (US) | 2023-12-21 | — | — | US | disclosed |
| WO-2021153720-A1 | 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT | クミアイ化学工業株式会社 | 2021-08-05 | — | — | WO | disclosed |
| US-20180265519-A1 | TRICYCLIC PROTEASOME ACTIVITY ENHANCING COMPOUNDS | THE ASSAY DEPOT, INC. | 2018-09-20 | — | — | US | disclosed |
| EP-3233794-A1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ADT Pharmaceuticals, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| EP-3233071-A1 | METHOD OF TREATING OR PREVENTING RAS-MEDIATED DISEASES | ADT Pharmaceuticals, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| EP-3233070-A1 | RAS-INHIBITING INDENYL ACETAMIDE COMPOUNDS, COMPOSITIONS, AND USES | ADT Pharmaceuticals, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016099452-A1 | RAS-INHIBITING INDENYL ACETAMIDE COMPOUNDS, COMPOSITIONS, AND USES | ADT PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |
| US-4052413-A | STEREOSPECIFIC TOTAL STEROIDAL SYNTHESIS VIA SUBSTITUTED C/D-TRANS INDANONES | HOFFMANN-LA ROCHE, INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4049677-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMAN-LA ROCHE INC. (US) | 1977-09-20 | — | — | US | disclosed |
| US-4048195-A | Process of synthesizing substituted indanones | HOFFMANN-LA ROCHE INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-3985733-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3984473-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3965117-A | Stereospecific total steroidal synthesis via substituted c/d-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3950389-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-04-13 | — | — | US | disclosed |