Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.81 |
| ▸ | ATRIP | Q8WXE1 | 20/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482247 | 0.95 | ATR (0.72) | ATRATRIP | |
| SCHEMBL17527543 | 0.90 | ATR (1.00) | ATRATRIPKCNH2 | |
| SCHEMBL30140516 | 0.90 | ATR (1.00) | ATRATRIPKCNH2 | |
| SCHEMBL20482406 | 0.90 | ATR (0.65) | ATRATRIP | |
| SCHEMBL18110036 | 0.88 | ATR (1.00) | ATRATRIP | |
| SCHEMBL18109996 | 0.85 | ATR (1.00) | ATRATRIPKCNH2 | |
| SCHEMBL17501610 | 0.84 | ATR (0.93) | ATRATRIP | |
| SCHEMBL18109971 | 0.83 | ATR (1.00) | ATRATRIP | |
| SCHEMBL20081952 | 0.82 | ATR (0.88) | ATRATRIP | |
| SCHEMBL23837748 | 0.80 | ATR (0.85) | ATRATRIPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177619-A1 | 2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES | Bayer Pharma Aktiengesellschaft (DE) | 2017-06-14 | — | — | EP | claimed |
| WO-2016020320-A1 | 2-(MORPHOLIN-4-YL)-L,7-NAPHTHYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-11 | — | — | WO | claimed |