Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3845683 | 0.95 | — | — | |
| SCHEMBL13661671 | 0.70 | — | — | |
| SCHEMBL28999010 | 0.67 | — | — | |
| SCHEMBL7895435 | 0.64 | — | — | |
| SCHEMBL15288588 | 0.64 | — | — | |
| SCHEMBL22618591 | 0.64 | — | — | |
| SCHEMBL20533648 | 0.64 | — | — | |
| Bromide SCHEMBL11364017 | 0.64 | — | — | |
| SCHEMBL1857875 | 0.61 | — | — | |
| Sulfuric Acid SCHEMBL21981415 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3179994-A1 | MODIFIED MITO-METFORMIN COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF | The Medical College of Wisconsin, Inc. (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016025725-A1 | MODIFIED MITO-METFORMIN COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2016-02-18 | — | — | WO | disclosed |