Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126970 | 0.95 | — | — | |
| SCHEMBL2058760 | 0.95 | CA5A (0.46) | — | |
| SCHEMBL1904 | 0.95 | — | — | |
| SCHEMBL7587151 | 0.91 | — | — | |
| SCHEMBL20583855 | 0.91 | — | — | |
| Methyl Alcohol SCHEMBL23421569 | 0.91 | — | — | |
| SCHEMBL20533683 | 0.91 | — | — | |
| SCHEMBL20533648 | 0.91 | — | — | |
| SCHEMBL22581624 | 0.91 | — | — | |
| SCHEMBL6917272 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287342-A | 2,4,6-Trihalo-5-alkyl-and 5-alkenylsulphonylpyrimidines | CIBA-GEIGY CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |
| US-4188483-A | 5-Alkylsulphonyl- and 5-alkenylsulphonylbarbituric acids and derivatives thereof | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |