Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 20/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17502282 | 0.95 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502277 | 0.91 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502254 | 0.80 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502310 | 0.79 | KCNH2 (1.00) | KCNH2 | |
| Hydrochloric Acid SCHEMBL21802309 | 0.79 | KCNH2 (0.98) | KCNH2 | |
| SCHEMBL17502274 | 0.77 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502262 | 0.76 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502209 | 0.76 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL19211436 | 0.76 | RXRA (0.70) | KCNH2 | |
| SCHEMBL17502333 | 0.75 | KCNH2 (1.00) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180329-A1 | TRIAZOLES AS NR2B RECEPTOR INHIBITORS | Janssen Pharmaceuticals, Inc. (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016025917-A1 | TRIAZOLES AS NR2B RECEPTOR INHIBITORS | Janssen Pharmaceuticals, Inc. (US) | 2016-02-18 | — | — | WO | disclosed |