Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17519220 | 0.87 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL21442550 | 0.87 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL21433374 | 0.82 | NR1H2 (0.60) | NR1H2NR1H3 | |
| SCHEMBL21433371 | 0.82 | NR1H2 (0.60) | NR1H2NR1H3 | |
| SCHEMBL21433339 | 0.81 | NR1H2 (0.74) | NR1H2NR1H3 | |
| SCHEMBL21433337 | 0.81 | NR1H2 (0.74) | NR1H2NR1H3 | |
| SCHEMBL2224887 | 0.75 | NR1H2 (0.45) | NR1H2NR1H3 | |
| SCHEMBL29252729 | 0.75 | AGTR2 (0.48) | NR1H2NR1H3 | |
| SCHEMBL673259 | 0.74 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL11963285 | 0.74 | NR1H2 (0.44) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177617-A1 | PIPERAZINE DERIVATIVES AS LIVER X RECEPTOR MODULATORS | Vitae Pharmaceuticals, Inc. (US) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016022521-A1 | PIPERAZINE DERIVATIVES AS LIVER X RECEPTOR MODULATORS | VITAE PHARMACEUTICALS, INC. (US) | 2016-02-11 | — | — | WO | disclosed |