SCHEMBL17505178

SCHEMBL17505178

CCCc1cc2cccc(C)c2[nH]c1=O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.61
ALDH1A1 P00352 8/20 0.61
HSD17B10 Q99714 3/20 0.61
HPGD P15428 2/20 0.61
NPSR1 Q6W5P4 1/20 0.61
KMT2A Q03164 1/20 0.61
DAO P14920 1/20 0.58
DDO Q99489 1/20 0.58
GLA P06280 1/20 0.56
RXFP1 Q9HBX9 2/20 0.56
TSHR P16473 1/20 0.56
ATM Q13315 3/20 0.51
LMNA P02545 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
USP2 O75604 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12559601 0.78 DAO (0.71) KDM4EALDH1A1HSD17B10HPGDNPSR1
SCHEMBL4072838 0.77 KDM4E (0.61) KDM4EALDH1A1HSD17B10HPGDNPSR1
Hydrochloric Acid SCHEMBL9432255 0.76 DAO (0.55) KDM4EALDH1A1HSD17B10HPGDNPSR1
SCHEMBL13349416 0.76 KDM4E (0.59) KDM4EALDH1A1HSD17B10HPGDNPSR1
SCHEMBL4745410 0.75 RXFP1 (0.69) KDM4EALDH1A1HSD17B10HPGDNPSR1
SCHEMBL10776370 0.74 DAO (0.56) KDM4EALDH1A1HSD17B10HPGDNPSR1
SCHEMBL10594689 0.74 BRD4 (0.51) KDM4EALDH1A1HSD17B10HPGDNPSR1
SCHEMBL24970979 0.73 DAO (0.65) KDM4EALDH1A1HSD17B10HPGDNPSR1
SCHEMBL9431998 0.73 DAO (0.65) KDM4EALDH1A1HSD17B10HPGDNPSR1
SCHEMBL16767856 0.73 DAO (1.00) KDM4EALDH1A1HSD17B10HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016022915-A1 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) 2016-02-11 WO disclosed