Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.65 |
| ▸ | DDO | Q99489 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12559601 | 0.83 | DAO (0.71) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL24970979 | 0.79 | DAO (0.65) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL31378942 | 0.79 | DAO (0.65) | DAODDOKDM4EPDE4APDE4B | |
| SCHEMBL16767856 | 0.79 | DAO (1.00) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL31378708 | 0.79 | DAO (0.65) | DAODDOPDE4APDE4BPDE4C | |
| SCHEMBL30939499 | 0.77 | DAO (0.53) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL831363 | 0.76 | DAO (0.61) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL4071083 | 0.76 | DAO (0.61) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9264392 | 0.75 | DAO (0.64) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL17505178 | 0.73 | KDM4E (0.61) | DAODDOKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |