Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 10/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | ESRRG | P62508 | 13/20 | 0.54 |
| ▸ | ESRRB | O95718 | 4/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523633 | 0.88 | ESRRB (0.53) | GAACYP19A1ESR1ESR2ESRRG | |
| SCHEMBL17523670 | 0.86 | CYP19A1 (0.54) | GAACYP19A1ESR1ESR2ESRRG | |
| SCHEMBL17523667 | 0.86 | CYP19A1 (0.50) | GAACYP19A1ESR1ESR2ESRRG | |
| SCHEMBL17523663 | 0.85 | CYP19A1 (0.55) | GAACYP19A1ESR1ESR2ESRRG | |
| SCHEMBL17523660 | 0.84 | ESRRG (0.53) | GAACYP19A1ESR1ESR2ESRRG | |
| SCHEMBL17523658 | 0.84 | ESRRG (0.53) | GAACYP19A1ESR1ESR2ESRRG | |
| SCHEMBL17523662 | 0.82 | EPHX1 (0.51) | GAACYP19A1ESR1ESR2ESRRG | |
| SCHEMBL17523634 | 0.81 | CYP19A1 (0.65) | GAACYP19A1ESR1ESR2ESRRG | |
| SCHEMBL19182067 | 0.81 | CYP19A1 (0.65) | GAACYP19A1ESR1ESR2ESRRG | |
| SCHEMBL18284476 | 0.81 | ESR1 (0.67) | CYP19A1ESR1ESR2ESRRGHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217914-A1 | Novel Triarylethylene Compounds and Methods Using Same | THE PENN STATE RESEARCH FOUNDATION | 2017-08-03 | — | — | US | disclosed |
| WO-2016022325-A1 | NOVEL TRIARYLETHYLENE COMPOUNDS AND METHODS USING SAME | THE PENN STATE RESEARCH FOUNDATION (US) | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217914-A1 | Novel Triarylethylene Compounds and Methods Using Same | CYP46A1, GSTA2, GSTA1 | GAA 253/4885CYP19A1 34/4885ESR1 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.