SCHEMBL17507243

SCHEMBL17507243

Cn1c2ccccc2c2cc(-c3cccc4c3oc3nc5ccccc5n34)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 3/20 0.38
KDM4E B2RXH2 5/20 0.36
HSD17B10 Q99714 4/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GPR3 P46089 1/20 0.36
BMX P51813 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PTGER4 P35408 3/20 0.35
FAAH O00519 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
CYP2C19 P33261 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17507424 0.87 KDM4E (0.39) FLT3KDM4EHSD17B10MAPTALDH1A1
SCHEMBL20041631 0.84 FLT3 (0.40) FLT3KDM4EMAPTALDH1A1HPGD
SCHEMBL20735396 0.84 FLT3 (0.37) FLT3KDM4EHSD17B10MAPTALDH1A1
SCHEMBL17507386 0.83 NPC1 (0.41) FLT3KDM4EMAPTALDH1A1HPGD
SCHEMBL20697969 0.83 FLT3 (0.36) FLT3KDM4EHSD17B10MAPTALDH1A1
SCHEMBL20041677 0.81 NPC1 (0.45) KDM4EHSD17B10MAPTALDH1A1HPGD
SCHEMBL17507246 0.81 FLT3 (0.39) FLT3KDM4EHSD17B10MAPTALDH1A1
SCHEMBL20041411 0.81 TOP2A (0.36) FLT3KDM4EHSD17B10MAPTALDH1A1
SCHEMBL20041679 0.80 FLT3 (0.41) FLT3KDM4EHSD17B10MAPTALDH1A1
SCHEMBL20041421 0.80 TP53 (0.45) FLT3HSD17B10MAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2982676-B1 Benzimidazo[2,1-B]benzoxazoles for electronic applications IDEMITSU KOSAN CO (JP) 2018-04-11 EP disclosed
EP-2982676-A1 Benzimidazo[2,1-B]benzoxazoles for electronic applications Idemitsu Kosan Co., Ltd. (JP) 2016-02-10 EP disclosed