SCHEMBL20041679

SCHEMBL20041679

Cc1ccc2oc3ccc(-c4cccc5c4oc4nc6ccccc6n45)cc3c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 4/20 0.41
FAAH O00519 1/20 0.38
HPGD P15428 4/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
KDM4E B2RXH2 4/20 0.36
POLB P06746 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
ALDH1A1 P00352 3/20 0.35
TP53 P04637 2/20 0.35
HSD17B10 Q99714 1/20 0.35
BMX P51813 2/20 0.34
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
PIM3 Q86V86 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17507386 0.90 NPC1 (0.41) FLT3FAAHHPGDNPC1RAB9A
SCHEMBL20041681 0.88 FLT3 (0.40) FLT3HPGDNPC1RAB9AKDM4E
SCHEMBL20041416 0.86 FLT3 (0.41) FLT3FAAHHPGDNPC1RAB9A
SCHEMBL17507246 0.85 FLT3 (0.39) FLT3HPGDNPC1RAB9AKDM4E
SCHEMBL20041421 0.85 TP53 (0.45) FLT3HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL20041423 0.84 NPC1 (0.42) FLT3HPGDNPC1RAB9AKDM4E
SCHEMBL17507339 0.84 FLT3 (0.45) FLT3HPGDNPC1RAB9AKDM4E
SCHEMBL20041533 0.83 TP53 (0.43) FLT3HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL20041619 0.82 TP53 (0.43) FLT3HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL20041625 0.81 NPC1 (0.41) FLT3FAAHHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2982676-B1 Benzimidazo[2,1-B]benzoxazoles for electronic applications IDEMITSU KOSAN CO (JP) 2018-04-11 EP disclosed