Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19563641 | 0.90 | SLC6A4 (0.43) | NPSR1ALDH1A1SLC6A4ERN1MRGPRX4 | |
| SCHEMBL1199311 | 0.85 | NPSR1 (0.61) | NPSR1LMNAGAAKMT2AALDH1A1 | |
| SCHEMBL19563626 | 0.83 | SCN8A (0.46) | KMT2AALDH1A1CYP1A2CYP2C19HPGD | |
| SCHEMBL1201334 | 0.83 | NPSR1 (0.61) | NPSR1LMNAGAAKMT2AALDH1A1 | |
| SCHEMBL24631610 | 0.83 | ALDH1A1 (0.55) | NPSR1LMNAGAAKMT2AALDH1A1 | |
| SCHEMBL19524197 | 0.82 | ERN1 (0.42) | NPSR1ALDH1A1HPGDSLC6A4ERN1 | |
| SCHEMBL5992341 | 0.82 | SCN8A (0.47) | KMT2AALDH1A1CYP1A2CYP2C19HPGD | |
| SCHEMBL19563616 | 0.81 | SCN10A (0.47) | — | |
| SCHEMBL4440723 | 0.81 | MEN1 (0.48) | KMT2ASMN1; SMN2TSHRSLC6A4MRGPRX4 | |
| SCHEMBL19524207 | 0.81 | SCN8A (0.45) | NPSR1ALDH1A1SLC6A4ERN1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016019588-A1 | OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE | THE BROAD INSTITUTE, INC. (US) | 2016-02-11 | — | — | WO | disclosed |