Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12122760 | 0.81 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL9339489 | 0.72 | CA12 (0.53) | CYP1A2CYP3A4CYP2C19KDM4EMEN1 | |
| SCHEMBL2127151 | 0.72 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL30254863 | 0.72 | ERBB2 (0.42) | CYP1A2CYP2C19SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL22904451 | 0.72 | ERBB2 (0.42) | CYP1A2CYP2C19SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL9359794 | 0.71 | KDM4E (0.54) | CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL9746057 | 0.70 | KDM4E (0.53) | CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL12122765 | 0.70 | TLR8 (0.58) | CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL9361407 | 0.70 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL31757251 | 0.70 | AR (0.56) | CYP1A2CYP3A4CYP2C19EPAS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534456-B2 | Heterocyclyl pyridines as novel fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 2026-01-27 | — | — | US | disclosed |
| US-20230295138-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-21 | — | — | US | disclosed |
| CN-116157397-A | Heterocyclylpyridines as novel fungicides | 拜耳公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-4161914-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | Bayer Aktiengesellschaft (DE) | 2023-04-12 | — | — | EP | disclosed |
| WO-2016021742-A1 | HETEROCYCLIC COMPOUNDS AS EP4 RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295138-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | PNPO, CBR3, HPD | CYP1A2 100/4885CYP3A4 38/4885CYP2C19 272/4885 |
| US-12534456-B2 | Heterocyclyl pyridines as novel fungicides | CBR1, CBR3, NOX1 | CYP1A2 57/4885CYP3A4 210/4885CYP2C19 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.