Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.75 |
| ▸ | MAPT | P10636 | 10/20 | 0.75 |
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | LMNA | P02545 | 9/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14819072 | 1.00 | MEN1 (0.75) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| Salubrinal SCHEMBL6477833 | 0.86 | MEN1 (1.00) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| Salubrinal SCHEMBL17360638 | 0.86 | MEN1 (1.00) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| Salubrinal SCHEMBL6477826 | 0.86 | MEN1 (1.00) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL14819076 | 0.86 | MEN1 (0.78) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL14819077 | 0.81 | MEN1 (0.52) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL15033093 | 0.79 | KMT2A (0.70) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL14819086 | 0.79 | MAPT (0.47) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL14819045 | 0.78 | MEN1 (0.56) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL14782069 | 0.78 | MEN1 (0.84) | MEN1KMT2AMAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439881-B2 | Acrylamide compounds and use thereof for inhibiting apoptosis | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-09-13 | — | — | US | disclosed |
| US-20160038445-A1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038445-A1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | BAX, API5, BCL2 | MEN1 4214/4885KMT2A 4693/4885MAPT 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.