Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.63 |
| ▸ | CNR1 | P21554 | 2/20 | 0.63 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | BUB1 | O43683 | 5/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435774 | 0.86 | CNR1 (0.54) | CNR2CNR1PTGER4ACHELMNA | |
| SCHEMBL16122909 | 0.81 | CNR2 (0.66) | CNR2CNR1PTGER4P2RX4BUB1 | |
| SCHEMBL30415447 | 0.81 | CNR2 (0.66) | CNR2CNR1PTGER4P2RX4BUB1 | |
| SCHEMBL516208 | 0.81 | CNR2 (0.66) | CNR2CNR1PTGER4P2RX4BUB1 | |
| SCHEMBL19793130 | 0.81 | CNR2 (0.66) | CNR2CNR1PTGER4P2RX4BUB1 | |
| SCHEMBL927918 | 0.80 | CNR1 (0.64) | CNR2CNR1PTGER4P2RX4BUB1 | |
| SCHEMBL12327729 | 0.77 | CNR2 (0.62) | CNR2CNR1PTGER4P2RX4BUB1 | |
| SCHEMBL31512385 | 0.77 | CNR2 (0.62) | CNR2CNR1PTGER4P2RX4BUB1 | |
| SCHEMBL14842958 | 0.77 | CNR2 (0.62) | CNR2CNR1PTGER4P2RX4BUB1 | |
| SCHEMBL9917500 | 0.77 | CNR2 (1.00) | CNR2CNR1PTGER4P2RX4BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160046610-A1 | 3-HETEROARYL SUBSTITUTED INDAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046610-A1 | 3-HETEROARYL SUBSTITUTED INDAZOLES | BUB1, BUB1B, BUB3 | CNR2 3787/4885CNR1 3014/4885PTGER4 4847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.