Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.45 |
| ▸ | ATXN2 | Q99700 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | RHOC | P08134 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129788 | 0.88 | ENPP2 (0.42) | ENPP2ATXN2SIGMAR1RHOCRHOA | |
| SCHEMBL16103009 | 0.88 | ENPP2 (0.45) | ENPP2ATXN2SIGMAR1 | |
| SCHEMBL16099740 | 0.86 | ENPP2 (0.43) | ENPP2ATXN2KMT2AALDH1A1GAA | |
| SCHEMBL16129736 | 0.82 | ENPP2 (0.43) | ENPP2ATXN2KMT2AHPGDTMEM97 | |
| SCHEMBL16100076 | 0.79 | TACR1 (0.43) | ENPP2ATXN2KMT2AHPGDSIGMAR1 | |
| SCHEMBL16129639 | 0.78 | ENPP2 (0.45) | ENPP2ATXN2EPHX2TMEM97SIGMAR1 | |
| SCHEMBL16099892 | 0.78 | ENPP2 (0.43) | ENPP2ATXN2 | |
| SCHEMBL16102966 | 0.76 | ENPP2 (0.40) | ENPP2ATXN2ALDH1A1NPC1RAB9A | |
| SCHEMBL16093852 | 0.76 | ENPP2 (0.47) | ENPP2ATXN2SIGMAR1 | |
| SCHEMBL16129734 | 0.76 | MEN1 (0.39) | ENPP2ATXN2KMT2AEPHX2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039825-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC. | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039825-A1 | S1P AND/OR ATX MODULATING AGENTS | ENPP2, S1PR1, S1PR2 | ENPP2 1/4885ATXN2 110/4885KMT2A 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.