Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22849936 | 0.89 | SLC16A3 (0.64) | SLC16A3CNR1CNR2ACHESCN8A | |
| SCHEMBL929060 | 0.86 | SLC16A3 (0.59) | SLC16A3CNR1CNR2ACHESCN8A | |
| SCHEMBL929474 | 0.85 | SLC16A3 (0.61) | SLC16A3CNR1CNR2ACHESCN8A | |
| SCHEMBL29562290 | 0.84 | SLC16A3 (0.57) | SLC16A3CNR1CNR2ACHESCN8A | |
| SCHEMBL927053 | 0.84 | SLC16A3 (0.57) | SLC16A3CNR1CNR2ACHESCN8A | |
| SCHEMBL22849913 | 0.83 | SLC16A3 (0.62) | SLC16A3CNR1CNR2ACHESCN8A | |
| SCHEMBL1603187 | 0.83 | CYP1A2 (0.61) | SLC16A3CNR1CNR2ACHESCN8A | |
| SCHEMBL927728 | 0.83 | SLC16A3 (0.58) | SLC16A3CNR1CNR2ACHESCN8A | |
| SCHEMBL1652008 | 0.83 | SLC16A3 (0.58) | SLC16A3CNR1CNR2ACHESCN8A | |
| Hydrochloric Acid SCHEMBL1603361 | 0.82 | POLB (0.62) | SLC16A3CNR1CNR2ACHESCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254870-B1 | 1-BENZYL-3-HYDROXYMETHYLINDAZOLE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF MCP-1, CX3CR1 | ACRAF (IT) | 2016-02-24 | — | — | EP | disclosed |