SCHEMBL22849913

SCHEMBL22849913

CCOCc1nn(Cc2ccccc2)c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC16A3 O15427 1/20 0.62
▸ CNR1 P21554 3/20 0.56
▸ CNR2 P34972 3/20 0.56
▸ ACHE P22303 2/20 0.56
▸ SCN8A Q9UQD0 2/20 0.49
▸ F2RL3 Q96RI0 1/20 0.49
▸ PDE5A O76074 6/20 0.48
▸ CYP1A2 P05177 3/20 0.48
▸ CYP2D6 P10635 3/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ GUCY1B2 O75343 1/20 0.48
▸ CHRM2 P08172 1/20 0.48
▸ HTR1A P08908 1/20 0.48
▸ ADRA2A P08913 1/20 0.48
▸ CHRM1 P11229 1/20 0.48
▸ DRD1 P21728 1/20 0.48
▸ SLC6A2 P23975 1/20 0.48
▸ SLC6A4 P31645 1/20 0.48
▸ GUCY1A2 P33402 1/20 0.48
▸ ADRA1A P35348 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22849936 0.91 SLC16A3 (0.64) SLC16A3CNR1CNR2ACHESCN8A
SCHEMBL17510202 0.83 SLC16A3 (0.59) SLC16A3CNR1CNR2ACHESCN8A
SCHEMBL929060 0.83 SLC16A3 (0.59) SLC16A3CNR1CNR2ACHESCN8A
SCHEMBL8373357 0.83 SLC16A3 (0.58) SLC16A3CNR1CNR2ACHESCN8A
SCHEMBL1603187 0.83 CYP1A2 (0.61) SLC16A3CNR1CNR2ACHESCN8A
Hydrochloric Acid SCHEMBL1603361 0.82 POLB (0.62) SLC16A3CNR1CNR2ACHESCN8A
Hydrochloric Acid SCHEMBL29562116 0.82 POLB (0.62) SLC16A3CNR1CNR2ACHESCN8A
SCHEMBL1651003 0.82 SLC16A3 (0.64) SLC16A3CNR1CNR2ACHESCN8A
SCHEMBL22849648 0.82 SLC16A3 (0.75) SLC16A3CNR1CNR2ACHESCN8A
SCHEMBL29562290 0.81 SLC16A3 (0.57) SLC16A3CNR1CNR2ACHESCN8A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025859-A1 PROCESSES OF MAKING 2-((1-BENZYL-1H-INDAZOL-3-YL)METHOXY)-2-METHYLPROPANOIC ACID AND ITS DERIVATIVES Translatum Medicus Inc. (CA) 2024-01-25 — — US disclosed
US-20240025859-A1 PROCESSES OF MAKING 2-((1-BENZYL-1H-INDAZOL-3-YL)METHOXY)-2-METHYLPROPANOIC ACID AND ITS DERIVATIVES Translatum Medicus Inc. (CA) 2024-01-25 — — US disclosed
US-11753382-B2 Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives Translatum Medicus Inc. (CA) 2023-09-12 — — US disclosed
US-11753382-B2 Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives Translatum Medicus Inc. (CA) 2023-09-12 — — US disclosed
WO-2020261158-A1 PROCESSES OF MAKING 2-((1-BENZYL-1H-INDAZOL-3-YL)METHOXY)-2-METHYLPROPANOIC ACID AND ITS DERIVATIVES Translatum Medicus Inc. (CA) 2020-12-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11753382-B2 Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives PCMT1, ICMT, FNTA SLC16A3 466/4885CNR1 3751/4885CNR2 2883/4885
US-20240025859-A1 PROCESSES OF MAKING 2-((1-BENZYL-1H-INDAZOL-3-YL)METHOXY)-2-METHYLPROPANOIC ACID AND ITS DERIVATIVES PCMT1, ICMT, FNTA SLC16A3 466/4885CNR1 3751/4885CNR2 2883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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