Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 11/20 | 0.59 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16151129 | 1.00 | CASR (0.59) | CASRCNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5082528 | 0.85 | CASR (0.71) | CASRSMN1; SMN2EPHX2 | |
| SCHEMBL5082519 | 0.85 | CASR (0.71) | CASRSMN1; SMN2EPHX2 | |
| SCHEMBL25760427 | 0.80 | CASR (0.73) | CASRNPC1RAB9A | |
| SCHEMBL14471883 | 0.80 | CASR (0.73) | CASRNPC1RAB9A | |
| SCHEMBL9404761 | 0.80 | GRIK1 (0.46) | NPC1 | |
| SCHEMBL19234900 | 0.80 | SLC7A5 (0.54) | CNR1NPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL19234894 | 0.80 | SLC7A5 (0.54) | CNR1NPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL16552433 | 0.80 | CASR (0.67) | CASRCNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3448862 | 0.78 | CASR (0.64) | CASRCNR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2023-09-12 | — | — | US | disclosed |
| US-11629171-B2 | Beta-hairpin peptidomimetics | SPEXIS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| CN-115093463-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3201219-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3201218-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-03 | — | — | EP | disclosed |
| CN-105324390-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-10-19 | — | — | CN | disclosed |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | SPEXIS AG (CH) | 2021-09-16 | — | — | US | disclosed |
| CN-105849119-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-01-19 | — | — | CN | disclosed |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2020-11-10 | — | — | US | disclosed |
| CN-111770932-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2020-10-13 | — | — | CN | disclosed |
| US-20180072776-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2018-03-15 | — | — | US | disclosed |
| US-20180072775-A1 | Beta-Hairpin Peptidomimetics | POLYPHOR AG (CH) | 2018-03-15 | — | — | US | disclosed |
| US-20180044380-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2018-02-15 | — | — | US | disclosed |
| US-9850284-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2017-12-26 | — | — | US | disclosed |
| US-20170253634-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2017-09-07 | — | — | US | disclosed |
| EP-3201218-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2017-08-09 | — | — | EP | disclosed |
| US-20170218026-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2017-08-03 | — | — | US | disclosed |
| WO-2016050360-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-04-07 | — | — | WO | disclosed |
| US-20160060298-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-03-03 | — | — | US | disclosed |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044380-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, BACE1, C1S | CASR 1311/4885CNR1 3342/4885NPC1 4103/4885 |
| US-20170253634-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, BACE1, C1S | CASR 1311/4885CNR1 3342/4885NPC1 4103/4885 |
| US-20170218026-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, BACE1, C1S | CASR 1352/4885CNR1 3370/4885NPC1 4084/4885 |
| US-20160060298-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, C1S, BACE1 | CASR 1294/4885CNR1 3645/4885NPC1 4496/4885 |
| US-11629171-B2 | Beta-hairpin peptidomimetics | POLL, POLQ, HBZ | CASR 907/4885CNR1 4690/4885NPC1 4602/4885 |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | C1S, POLL, BACE1 | CASR 1408/4885CNR1 3638/4885NPC1 3953/4885 |
| US-20180072775-A1 | Beta-Hairpin Peptidomimetics | POLQ, POLL, POLM | CASR 2102/4885CNR1 4858/4885NPC1 4582/4885 |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, POLQ, POLM | CASR 1037/4885CNR1 4708/4885NPC1 4663/4885 |
| US-20180072776-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, BACE1, C1S | CASR 1258/4885CNR1 3307/4885NPC1 4167/4885 |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLQ, POLL, POLM | CASR 2102/4885CNR1 4858/4885NPC1 4582/4885 |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLL, BACE1, C1S | CASR 1311/4885CNR1 3342/4885NPC1 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.