Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19378090 | 1.00 | CASP3 (0.48) | CASP3EPHX2KMT2AFABP7FABP5 | |
| SCHEMBL3123838 | 0.89 | CASP3 (0.51) | CASP3EPHX2KMT2AFABP7FABP5 | |
| SCHEMBL120613 | 0.84 | MDM4 (0.51) | CASP3EPHX2KMT2AMDM4TP53 | |
| SCHEMBL29907877 | 0.84 | MDM4 (0.51) | CASP3EPHX2KMT2AMDM4TP53 | |
| SCHEMBL2305506 | 0.84 | MDM4 (0.51) | CASP3EPHX2KMT2AMDM4TP53 | |
| SCHEMBL29872206 | 0.84 | MDM4 (0.51) | CASP3EPHX2KMT2AMDM4TP53 | |
| SCHEMBL29928500 | 0.84 | MDM4 (0.51) | CASP3EPHX2KMT2AMDM4TP53 | |
| SCHEMBL120601 | 0.84 | MDM4 (0.51) | CASP3EPHX2KMT2AMDM4TP53 | |
| SCHEMBL30532481 | 0.84 | MDM4 (0.51) | CASP3EPHX2KMT2AMDM4TP53 | |
| SCHEMBL13132526 | 0.84 | TP53 (0.44) | CASP3EPHX2KMT2AMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |