SCHEMBL17514548

SCHEMBL17514548

C=CCOc1cc(F)c(-c2[c]ccc(F)c2)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.36
CA12 O43570 5/20 0.35
CA1 P00915 5/20 0.35
CA9 Q16790 5/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
MAOA P21397 2/20 0.34
KAT6A Q92794 5/20 0.34
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR2A P28223 3/20 0.32
HTR2C P28335 3/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514592 0.86 GAA (0.38) MAOBCA12CA1CA9CA2
SCHEMBL17514544 0.78 MAOB (0.34) MAOBCA12CA1CA9CA2
SCHEMBL17514728 0.77 MAOB (0.36) MAOBCA12CA1CA9CA2
SCHEMBL17514466 0.77 MAOB (0.33) MAOBCA12CA1CA9CA2
SCHEMBL17514590 0.77 MAPT (0.35) MAOBCA12CA1CA9CA2
SCHEMBL17514649 0.76 KAT6A (0.40) MAOBCA12CA1CA9CA2
SCHEMBL17514651 0.76 MAOB (0.35) MAOBCA12CA1CA9CA2
SCHEMBL17514480 0.76 MAOB (0.35) MAOBCA12CA1CA9CA2
SCHEMBL17514523 0.75 HTR2C (0.34) MAOBCA12CA1CA9CA2
SCHEMBL17514512 0.75 MAOB (0.34) MAOBCA12CA1CA9CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed