Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 5/20 | 0.32 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA9 | Q16790 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514512 | 0.86 | MAOB (0.34) | MAOBADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL17514825 | 0.84 | MAOB (0.40) | MAOBADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL17514664 | 0.82 | MAOB (0.36) | MAOBADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL920851 | 0.80 | MAPT (0.41) | ADRA2AADRA2BADRA2CMAPTMEN1 | |
| SCHEMBL17514544 | 0.78 | MAOB (0.34) | MAOBADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL17514466 | 0.77 | MAOB (0.33) | MAOBADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL17514548 | 0.77 | MAOB (0.36) | MAOBADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL17514590 | 0.77 | MAPT (0.35) | MAOBADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL17514480 | 0.76 | MAOB (0.35) | MAOBADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL17514895 | 0.76 | HTR2C (0.33) | MAOBADRA2AADRA2BADRA2CMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016026830-A1 | NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | WO | disclosed |