SCHEMBL17514732

SCHEMBL17514732

N#Cc1cc(F)c(-c2c(Cl)[c]ccc2F)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 3/20 0.35
KIF11 P52732 1/20 0.32
CYP1A2 P05177 1/20 0.30
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17515035 0.89 EGLN2 (0.34) EGLN2KIF11GRM5
SCHEMBL17514505 0.83 EGLN2 (0.36) EGLN2KIF11
SCHEMBL17514682 0.82 EGLN2 (0.34) EGLN2KIF11GRM5
SCHEMBL17514908 0.81 EGLN2 (0.35) EGLN2
SCHEMBL17514784 0.80
SCHEMBL17514604 0.80 EGLN2 (0.36) EGLN2
SCHEMBL17514659 0.79 EGLN2 (0.34) EGLN2GRM5
SCHEMBL17514978 0.79 EGLN2 (0.34) EGLN2
SCHEMBL17514769 0.78 EGLN2 (0.36) EGLN2KIF11GRM5
SCHEMBL17514918 0.77 RAPGEF4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed