SCHEMBL17514895

SCHEMBL17514895

C=CCOc1cc(F)c(-c2cc(F)[c]c(Cl)c2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.33
HTR2B P41595 4/20 0.33
MAOB P27338 2/20 0.33
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514501 0.93 MAOB (0.34) HTR2CHTR2BMAOBADRA2AADRA2B
SCHEMBL17514664 0.90 MAOB (0.36) HTR2CHTR2BMAOBADRA2AADRA2B
SCHEMBL17514512 0.80 MAOB (0.34) HTR2CHTR2BMAOBADRA2AADRA2B
SCHEMBL17514646 0.77 CA12 (0.35) HTR2CHTR2BMAOBADRA2AADRA2B
SCHEMBL17514728 0.76 MAOB (0.36) MAOBADRA2AADRA2BADRA2CMAOA
SCHEMBL15066324 0.75 MEN1 (0.39) HTR2CHTR2BMAOBADRA2AADRA2B
SCHEMBL15067030 0.75 MEN1 (0.39) HTR2CHTR2BMAOBADRA2AADRA2B
SCHEMBL17514894 0.74 MEN1 (0.37) HTR2CHTR2BMAOBADRA2AADRA2B
SCHEMBL17514550 0.74 HTR2C (0.33) HTR2CHTR2BMAOBADRA2AADRA2B
SCHEMBL17514500 0.74 MEN1 (0.37) HTR2CHTR2BMAOBADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed