SCHEMBL17517853

SCHEMBL17517853

COCN([C@H](C)c1cccc(OCC2CC2)c1)S(=O)(=O)CC/C=C/CC1CCC(=O)NC1=O

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DUT P33316 18/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19558244 0.88 DUT (0.46) DUT
SCHEMBL17517855 0.85 DUT (0.43) DUT
SCHEMBL17517854 0.84 DUT (0.47) DUT
SCHEMBL17520397 0.83 DUT (0.46) DUT
SCHEMBL30017458 0.83 DUT (0.64) DUT
SCHEMBL20560888 0.83 DUT (0.64) DUT
SCHEMBL15870819 0.83 DUT (0.64) DUT
SCHEMBL18377590 0.83 DUT (0.64) DUT
SCHEMBL18374432 0.79 DUT (0.53) DUT
SCHEMBL23473235 0.76 DUT (0.46) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889563-B2 Deoxyuridine triphosphatase inhibitors UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2021-01-12 — — US disclosed
US-20190270719-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS PRESTWICK CHEMICAL, SAS (FR) 2019-09-05 — — US disclosed
US-10227326-B2 Deoxyuridine triphosphatase inhibitors UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2019-03-12 — — US disclosed
US-20180155319-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS UNIVERSITY OF SOUTHERN CALIFORNIA 2018-06-07 — — US disclosed
US-20180155319-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS UNIVERSITY OF SOUTHERN CALIFORNIA 2018-06-07 — — US disclosed
US-9809571-B2 Deoxyuridine triphosphatase inhibitors UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2017-11-07 — — US disclosed
US-9809571-B2 Deoxyuridine triphosphatase inhibitors UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2017-11-07 — — US disclosed
US-20160039788-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS UNIVERSITY OF SOUTHERN CALIFORNIA 2016-02-11 — — US disclosed
US-20160039788-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS UNIVERSITY OF SOUTHERN CALIFORNIA 2016-02-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190270719-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS DUT, TYMP, DPYD DUT 1/4885
US-20180155319-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS DUT, TYMP, DPYD DUT 1/4885
US-10889563-B2 Deoxyuridine triphosphatase inhibitors DUT, TYMP, DPYD DUT 1/4885
US-10227326-B2 Deoxyuridine triphosphatase inhibitors DUT, TYMP, DPYD DUT 1/4885
US-20160039788-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS DUT, TYMP, DPYD DUT 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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