SCHEMBL17520293

SCHEMBL17520293

Fc1c(I)ccc(C(F)(F)F)c1F

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.38
NOTUM Q6P988 1/20 0.35
KIF11 P52732 2/20 0.32
MPL P40238 1/20 0.30
CFTR P13569 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30730977 1.00 PDE2A (0.38) PDE2ANOTUMKIF11MPLCFTR
SCHEMBL28453327 0.84 PDE2A (0.45) PDE2AKIF11MPL
SCHEMBL25037002 0.79 PDE2A (0.35) PDE2ANOTUMKIF11MPL
SCHEMBL30364632 0.78 MPL (0.40) NOTUMKIF11MPL
SCHEMBL12326344 0.78 MPL (0.40) NOTUMKIF11MPL
SCHEMBL1425995 0.78 NOTUM (0.31) NOTUM
SCHEMBL29559941 0.78 NOTUM (0.31) NOTUM
SCHEMBL20417256 0.76
SCHEMBL6723791 0.74 KIF11 (0.39) KIF11
SCHEMBL5109158 0.74 KIF11 (0.39) NOTUMKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111094512-B Liquid crystal medium and liquid crystal display comprising same 默克专利股份有限公司 2024-01-09 CN disclosed
EP-3679111-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2023-11-01 EP disclosed
EP-3679111-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2023-11-01 EP disclosed
US-20220228065-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2022-07-21 US disclosed
US-11326102-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2022-05-10 US disclosed
US-11326102-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2022-05-10 US disclosed
US-20200385636-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2020-12-10 US disclosed
US-20200385636-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2020-12-10 US disclosed
EP-3679111-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2020-07-15 EP disclosed
CN-111094512-A Liquid crystal medium and liquid crystal display comprising same 默克专利股份有限公司 2020-05-01 CN disclosed
WO-2019048444-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2019-03-14 WO disclosed
WO-2019048444-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2019-03-14 WO disclosed
WO-2016022902-A1 DIAZEPANE DERIVATIVES AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2016-02-11 WO disclosed