SCHEMBL17520347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17520359	0.95	KDR (0.87)	KDRFGFR1FLT1EGFRFLT4
	SCHEMBL17520350	0.95	KDR (0.82)	KDRFGFR1FLT1EGFRFLT4
	SCHEMBL17520326	0.95	EGFR (0.85)	KDRFGFR1FLT1EGFRFLT4
	SCHEMBL7864675	0.94	KDR (0.90)	KDRFGFR1FLT1EGFRFLT4
	Hydrochloric Acid SCHEMBL7866132	0.93	EGFR (0.92)	KDRFGFR1FLT1EGFRFLT4
	SCHEMBL7859476	0.92	KDR (0.83)	KDRFGFR1FLT1EGFRFLT4
	Hydrochloric Acid SCHEMBL7870588	0.91	EGFR (0.81)	KDRFGFR1FLT1EGFRFLT4
	SCHEMBL19220768	0.91	KDR (0.82)	KDRFGFR1FLT1EGFRFLT4
	SCHEMBL1467348	0.90	FLT1 (1.00)	KDRFGFR1FLT1EGFRFLT4
	SCHEMBL5458741	0.90	KDR (0.75)	KDRFGFR1FLT1EGFRFLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.