SCHEMBL17520362

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11156	1.00	EGFR (1.00)	EGFRKDRFGFR1FLT1AURKA
	SCHEMBL11683	0.96	EGFR (0.92)	EGFRKDRFGFR1FLT1AURKA
	SCHEMBL18979111	0.96	EGFR (0.92)	EGFRKDRFGFR1FLT1AURKA
	SCHEMBL19220785	0.90	EGFR (0.82)	EGFRKDRFGFR1FLT1AURKA
	SCHEMBL12856430	0.89	EGFR (0.80)	EGFRKDRFGFR1FLT1ERBB2
	SCHEMBL7451584	0.87	FLT1 (1.00)	EGFRKDRFGFR1FLT1PDGFRB
	Hydrochloric Acid SCHEMBL7455267	0.86	FLT1 (0.98)	EGFRKDRFGFR1FLT1PDGFRB
	SCHEMBL19220767	0.86	EGFR (0.76)	EGFRKDRFGFR1FLT1ERBB2
	SCHEMBL13524614	0.85	EGFR (0.87)	EGFRKDRAURKAERBB2INSR
	SCHEMBL30520472	0.85	EGFR (0.87)	EGFRKDRAURKAERBB2INSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.