Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.80 |
| ▸ | FBP1 | P09467 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.61 |
| ▸ | FLT1 | P17948 | 1/20 | 0.61 |
| ▸ | CIT | O14578 | 1/20 | 0.60 |
| ▸ | GAK | O14976 | 1/20 | 0.60 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.60 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.60 |
| ▸ | STK17B | O94768 | 1/20 | 0.60 |
| ▸ | STK10 | O94804 | 1/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.60 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683 | 0.93 | EGFR (0.92) | EGFRFBP1KDRFGFR1FLT1 | |
| SCHEMBL18979111 | 0.93 | EGFR (0.92) | EGFRFBP1KDRFGFR1FLT1 | |
| SCHEMBL11156 | 0.89 | EGFR (1.00) | EGFRFBP1KDRFGFR1FLT1 | |
| SCHEMBL17520362 | 0.89 | EGFR (1.00) | EGFRFBP1KDRFGFR1FLT1 | |
| SCHEMBL19220767 | 0.83 | EGFR (0.76) | EGFRKDRFGFR1FLT1CIT | |
| SCHEMBL29577315 | 0.82 | FBP1 (0.78) | EGFRFBP1KDRERBB2FLT4 | |
| Hydrochloric Acid SCHEMBL2163107 | 0.81 | EGFR (0.72) | EGFRKDRFGFR1FLT1CIT | |
| SCHEMBL15217652 | 0.80 | FBP1 (0.78) | EGFRFBP1KDRERBB2FLT4 | |
| SCHEMBL29577645 | 0.80 | FBP1 (0.78) | EGFRFBP1KDRERBB2FLT4 | |
| Hydrochloric Acid SCHEMBL7455695 | 0.80 | FLT1 (0.91) | EGFRKDRFGFR1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | disclosed |