Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523301 | 1.00 | KDM1A (0.46) | KDM1ARCOR1CYP2C9CYP2C19RORC | |
| SCHEMBL17523295 | 0.94 | CYP2C9 (0.44) | KDM1ARCOR1CYP2C9CYP2C19RORC | |
| SCHEMBL17523304 | 0.94 | CYP2C9 (0.44) | KDM1ARCOR1CYP2C9CYP2C19RORC | |
| SCHEMBL17523290 | 0.90 | KDM1A (0.42) | KDM1ACYP2C19HSD11B1CYP3A4CYP2D6 | |
| SCHEMBL17523288 | 0.90 | KDM1A (0.42) | KDM1ACYP2C19HSD11B1CYP3A4CYP2D6 | |
| SCHEMBL17523298 | 0.87 | SLC6A9 (0.40) | KDM1ACYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL17523297 | 0.87 | SLC6A9 (0.40) | KDM1ACYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL17523300 | 0.86 | LIG1 (0.40) | KDM1ARCOR1CYP2C19RORCLIG1 | |
| SCHEMBL17523305 | 0.86 | LIG1 (0.40) | KDM1ARCOR1CYP2C19RORCLIG1 | |
| SCHEMBL17523291 | 0.81 | SLC6A9 (0.40) | KDM1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | KDM1A 3183/4885RCOR1 2801/4885CYP2C9 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.