Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SETDB1 | Q15047 | 5/20 | 0.45 |
| ▸ | VHL | P40337 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23279842 | 0.83 | F2 (0.53) | NPSR1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL4897153 | 0.78 | MCL1 (0.49) | ALDH1A1KDM4EP2RX7F2PRSS1 | |
| SCHEMBL20038391 | 0.75 | SLC6A4 (0.36) | KMT2AALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL19323056 | 0.74 | CYP2C9 (0.54) | NPSR1SETDB1VHLKMT2AMTNR1A | |
| SCHEMBL30421108 | 0.74 | CYP2C9 (0.54) | NPSR1SETDB1VHLKMT2AMTNR1A | |
| SCHEMBL16793671 | 0.72 | KLKB1 (0.39) | NPSR1SETDB1ALDH1A1KDM4EP2RX7 | |
| SCHEMBL7573152 | 0.72 | CCR1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30585580 | 0.72 | CCR1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20038385 | 0.72 | PDCD1LG2 (0.41) | NPSR1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL21193078 | 0.71 | SETDB1 (0.45) | NPSR1SETDB1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160046606-A1 | CXCR4 Receptor Antagonists | PROXIMAGEN LIMITED (GB) | 2016-02-18 | — | — | US | disclosed |
| US-20160046606-A1 | CXCR4 Receptor Antagonists | PROXIMAGEN LIMITED (GB) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046606-A1 | CXCR4 Receptor Antagonists | CXCR4, CXCR1, CXCR2 | NPSR1 18/4885SETDB1 4725/4885VHL 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.