Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585580 | 1.00 | CCR1 (0.40) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL14868199 | 0.81 | PDE10A (0.41) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL834352 | 0.80 | KDM4E (0.45) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL7115183 | 0.78 | PARP1 (0.37) | GRM1 | |
| SCHEMBL29674415 | 0.78 | KDM4E (0.48) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL15211213 | 0.78 | CCR1 (0.39) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL957406 | 0.78 | KDM4E (0.48) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL4325085 | 0.78 | CCR1 (0.39) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL18198244 | 0.78 | CCR1 (0.39) | CCR1RAB9ACCR5KDM4EALDH1A1 | |
| SCHEMBL1260062 | 0.78 | TYR (0.41) | CCR1RAB9ACCR5ALDH1A1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143185-B1 | METHOD FOR THE ELECTROCHEMICAL AMINATION AT BORON DOPED DIAMOND ANODES | COVESTRO DEUTSCHLAND AG (DE) | 2018-10-03 | — | — | EP | claimed |
| EP-3143185-A1 | METHOD FOR PRODUCING 1.5-DIAMINONAPHTHALENE AND 1-AMINO-5-NITRONAPHTHALENE BY DIRECT ELECTROCHEMICAL AMINATION OF NON-ACTIVATED OR DEACTIVATED AROMATIC SYSTEMS ON BORON-DOPED DIAMOND ANODES | Covestro Deutschland AG (DE) | 2017-03-22 | — | — | EP | claimed |
| WO-2015173221-A1 | METHOD FOR PRODUCING 1.5-DIAMINONAPHTHALENE AND 1-AMINO-5-NITRONAPHTHALENE BY DIRECT ELECTROCHEMICAL AMINATION OF NON-ACTIVATED OR DEACTIVATED AROMATIC SYSTEMS ON BORON-DOPED DIAMOND ANODES | COVESTRO DEUTSCHLAND AG (DE) | 2015-11-19 | — | — | WO | claimed |
| US-5696282-A | CATALYTIC REACTION OF A HYDROGEN SULFIDE OR MERCAPTAN WITH UNSATURATED CARBONYL OR CYANO COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1997-12-09 | — | — | US | claimed |
| US-4871848-A | OIL, GAS WELLS CORROSION INHIBITORS | THE DOW CHEMICAL COMPANY (US) | 1989-10-03 | — | — | US | claimed |
| US-4740320-A | REACTION OF NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPONENT, KETONE OR ALDEHYDE, AMINE OR POLYAMINE | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | claimed |
| US-4725373-A | CORROSION RESISTANCE FOR METAL TOOLS AND EQUIPMENT USED IN OIL AND GAS WELLS | THE DOW CHEMICAL COMPANY (US) | 1988-02-16 | — | — | US | claimed |
| US-20240043391-A1 | METHOD FOR PRODUCING ALKYLPYRAZINES | SYMRISE AG (DE) | 2024-02-08 | — | — | US | disclosed |
| US-20240018102-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | Lhotse Bio, Inc (US) | 2024-01-18 | — | — | US | disclosed |
| EP-4287848-A1 | METHOD FOR PRODUCING ALKYLPYRAZINES | Symrise AG (DE) | 2023-12-13 | — | — | EP | disclosed |
| CN-116806122-A | Process for the preparation of alkylpyrazine | 西姆莱斯有限公司 | 2023-09-26 | — | — | CN | disclosed |
| US-20230174532-A1 | METHODS FOR ANTAGONIZING A MELANOCORTIN 4 RECEPTOR | PFIZER INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-11643412-B2 | Melanocortin 4 receptor antagonists and uses thereof | PFIZER INC. (US) | 2023-05-09 | — | — | US | disclosed |
| EP-0725095-A1 | Process for producing a polymer of vinylic compounds | KURARAY CO., LTD. (JP) | 1996-08-07 | — | — | EP | disclosed |
| EP-0639181-A1 | PYRIDINE-SUBSTITUTED BENZYL ALCOHOLS AS LEUKOTRIENE ANTAGONISTS | MERCK FROSST CANADA INC. (CA) | 1995-02-22 | — | — | EP | disclosed |
| US-4871848-A | OIL, GAS WELLS CORROSION INHIBITORS | THE DOW CHEMICAL COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| US-4740320-A | REACTION OF NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPONENT, KETONE OR ALDEHYDE, AMINE OR POLYAMINE | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4725373-A | CORROSION RESISTANCE FOR METAL TOOLS AND EQUIPMENT USED IN OIL AND GAS WELLS | THE DOW CHEMICAL COMPANY (US) | 1988-02-16 | — | — | US | disclosed |
| US-4724003-A | Asphalt compositions containing anti-stripping additives prepared from hydrocarbyl substituted nitrogen-containing aromatic heterocyclic compounds, aldehydes or ketones and amines | THE DOW CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4676834-A | Novel compositions prepared from methyl substituted nitrogen-containing aromatic heterocyclic compounds and an aldehyde or ketone | THE DOW CHEMICAL COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018102-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | LPAR1, LPAR2, LPAR5 | CCR1 1102/4885RAB9A 1153/4885CCR5 1198/4885 |
| US-20230174532-A1 | METHODS FOR ANTAGONIZING A MELANOCORTIN 4 RECEPTOR | MC4R, MC2R, NPY4R | CCR1 687/4885RAB9A 1302/4885CCR5 456/4885 |
| US-11643412-B2 | Melanocortin 4 receptor antagonists and uses thereof | MC4R, MC3R, MC5R | CCR1 750/4885RAB9A 1602/4885CCR5 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.