Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | GLA | P06280 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525590 | 0.98 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL17525638 | 0.86 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL17525575 | 0.86 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL17525583 | 0.86 | MLLT1 (0.36) | KDM4EALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL17525653 | 0.86 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL17525639 | 0.86 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL14745591 | 0.86 | KDM4E (0.32) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL14745431 | 0.85 | KDM4E (0.32) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL17498136 | 0.85 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDHSD17B10ALOX5 | |
| SCHEMBL14757217 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025933-A2 | SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-02-18 | — | — | WO | disclosed |