Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 2/20 | 0.56 |
| ▸ | RUNX1 | Q01196 | 11/20 | 0.53 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179102 | 0.81 | CBFB (0.82) | CBFBRUNX1PDE10ATRPV1 | |
| SCHEMBL19228827 | 0.80 | CXCR3 (0.45) | CBFBCXCR3FGFR1TRPV1 | |
| SCHEMBL179101 | 0.80 | CBFB (0.63) | CBFBRUNX1TRPV1 | |
| SCHEMBL179096 | 0.80 | CBFB (0.63) | CBFBRUNX1TRPV1 | |
| SCHEMBL17525962 | 0.78 | RUNX1 (0.62) | CBFBRUNX1PDE10ATRPV1 | |
| SCHEMBL17525963 | 0.78 | RUNX1 (0.84) | CBFBRUNX1TRPV1 | |
| SCHEMBL17525960 | 0.77 | RUNX1 (0.84) | CBFBRUNX1PDE10A | |
| SCHEMBL17525970 | 0.76 | RUNX1 (0.69) | CBFBRUNX1 | |
| SCHEMBL21727103 | 0.75 | RUNX1 (0.63) | CBFBRUNX1TRPV1 | |
| SCHEMBL17525975 | 0.75 | RUNX1 (0.68) | CBFBRUNX1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180004-B1 | CANCER THERAPEUTICS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2021-01-06 | — | — | EP | disclosed |
| US-10562890-B2 | Cancer therapeutics | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2020-02-18 | — | — | US | disclosed |
| US-20170233375-A1 | CANCER THERAPEUTICS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2017-08-17 | — | — | US | disclosed |
| WO-2016025744-A1 | CANCER THERAPEUTICS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233375-A1 | CANCER THERAPEUTICS | RUNX1, CBFB, MCL1 | CBFB 2/4885RUNX1 1/4885CXCR3 1245/4885 |
| US-10562890-B2 | Cancer therapeutics | RUNX1, CBFB, MCL1 | CBFB 2/4885RUNX1 1/4885CXCR3 1245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.