Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525995 | 0.87 | MAPT (0.45) | MAPTMEN1KMT2AKDM4EG6PD | |
| SCHEMBL25367899 | 0.85 | MAPT (0.46) | MAPTMEN1KMT2AKDM4EG6PD | |
| SCHEMBL29474148 | 0.81 | CYP1A2 (0.53) | MAPTMEN1KMT2AKDM4EG6PD | |
| SCHEMBL17525997 | 0.80 | ALDH1A1 (0.45) | MAPTMEN1KMT2AKDM4EG6PD | |
| SCHEMBL10472840 | 0.80 | MAPT (0.46) | MAPTMEN1KMT2AKDM4EG6PD | |
| SCHEMBL3520372 | 0.78 | SMN1; SMN2 (0.48) | MAPTMEN1KMT2AKDM4EG6PD | |
| SCHEMBL30079683 | 0.77 | CYP1A2 (0.45) | MAPTMEN1KMT2AKDM4EG6PD | |
| SCHEMBL24823673 | 0.77 | CYP1A2 (0.45) | MAPTMEN1KMT2AKDM4EG6PD | |
| SCHEMBL6475603 | 0.77 | TSHR (0.49) | MAPTMEN1KMT2AKDM4EG6PD | |
| SCHEMBL31569258 | 0.77 | MAPT (0.43) | MAPTMEN1KMT2AKDM4EG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025744-A1 | CANCER THERAPEUTICS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-02-18 | — | — | WO | disclosed |