⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132758 | 1.00 | — | — | |
| SCHEMBL742837 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30461951 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL5565250 | 0.82 | — | — | |
| SCHEMBL28825344 | 0.74 | — | — | |
| SCHEMBL10420937 | 0.74 | ADH1B (0.37) | — | |
| SCHEMBL23635220 | 0.73 | — | — | |
| SCHEMBL19220821 | 0.73 | — | — | |
| Isobutyraldehyde SCHEMBL2635854 | 0.71 | ADH1B (0.38) | — | |
| Isobutyraldehyde SCHEMBL788159 | 0.71 | ADH1B (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195898-A1 | TREATMENT OF ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT USING GNRH-I ANALOGS AND ONE OR MORE OF ACETYLCHOLINESTERASE INHIBITORS AND NMDA RECEPTOR ANTAGONISTS | VOYAGER PHARMACEUTICAL CORPORATION (US) | 2011-08-11 | — | — | US | claimed |
| US-20100173838-A1 | NOVEL PROCESS FOR THE PREPARATION OF CYCLOSPORIN DERIVATIVES | VISKOV CHRISTIAN | 2010-07-08 | — | — | US | claimed |
| EP-1451209-A4 | TETRA-,PENTA-,HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LAB (US) | 2009-06-03 | — | — | EP | claimed |
| EP-1450840-A4 | DI-, TRI,- AND TETRA-PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LAB (US) | 2009-06-03 | — | — | EP | claimed |
| US-20080171736-A1 | Treatment of Alzheimer's Disease and Mild Cognitive impairment using GnRH-I analogs and one or more of acetylcholinesterase inhibitors and NMDA receptor antagonists | VOYAGER PHARMACEUTICAL CORPORATION | 2008-07-17 | — | — | US | claimed |
| US-20080071062-A1 | TETRA-, PENTA-, HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | HAVIV FORTUNA | 2008-03-20 | — | — | US | claimed |
| EP-1461356-A4 | HEXA-, HEPTA-, AND OCTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LAB (US) | 2007-12-12 | — | — | EP | claimed |
| US-20070213260-A1 | Novel process for the preparation of cyclosporin derivatives | AVENTIS PHARMA S.A. | 2007-09-13 | — | — | US | claimed |
| US-20070167376-A1 | Hexa-, Hepta-, and Octapeptides Having Antiangiogenic Activity | HAVIV FORTUNA | 2007-07-19 | — | — | US | claimed |
| US-7169888-B2 | Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2007-01-30 | — | — | US | claimed |
| US-4885276-A | IMMUNOSUPPRESSIVE AGENTS WITH DECREASED TOXICITY | MERCK & CO., INC. (US) | 1989-12-05 | — | — | US | claimed |
| WO-1989007450-A1 | LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | claimed |
| EP-0328090-A2 | LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |
| US-4798823-A | IMMUNOSUPPRESSIVE AGENTS | MERCK & CO., INC. (US) | 1989-01-17 | — | — | US | claimed |
| US-4775660-A | Treatment of breast cancer by combination therapy | LABRIE FERNAND (CA) | 1988-10-04 | — | — | US | claimed |
| US-4760053-A | Combination therapy for selected sex steroid dependent cancers | LABRIE FERNAND (CA) | 1988-07-26 | — | — | US | claimed |
| US-4659695-A | Method of treatment of prostate cancer | LABRIE FERNAND (CA) | 1987-04-21 | — | — | US | claimed |
| EP-0195015-A1 | PHARMACEUTICAL COMPOSITION FOR COMBINATION THERAPY OF HORMONE DEPENDENT CANCERS. | LABRIE FERNAND (CA) | 1986-09-24 | — | — | EP | claimed |
| EP-0188214-A2 | Novel growth hormone-releasing peptides and method of treating mammals therewith | The Administrators of The Tulane University Educational Fund (US) | 1986-07-23 | — | — | EP | claimed |
| WO-1986001105-A1 | PHARMACEUTICAL COMPOSITION FOR COMBINATION THERAPY OF HORMONE DEPENDENT CANCERS | LABRIE FERNAND (CA) | 1986-02-27 | — | — | WO | claimed |