Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 18/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11900440 | 0.91 | ALK (0.47) | ALKINSRROS1EGFR | |
| SCHEMBL11900724 | 0.84 | ALK (0.46) | ALKINSRROS1 | |
| SCHEMBL21709591 | 0.80 | ALK (0.51) | ALKINSRLRRK2 | |
| SCHEMBL11916339 | 0.79 | ALK (0.55) | ALKINSREGFRLRRK2 | |
| SCHEMBL19288567 | 0.78 | ALK (0.49) | ALKINSRROS1EGFRLRRK2 | |
| SCHEMBL17527454 | 0.78 | ALK (0.59) | ALKINSRROS1EGFRLRRK2 | |
| SCHEMBL19288528 | 0.76 | ALK (0.39) | ALKINSRROS1 | |
| SCHEMBL11901894 | 0.75 | ALK (0.59) | ALKINSRROS1EGFRLRRK2 | |
| SCHEMBL11900720 | 0.73 | ALK (0.46) | ALKINSRROS1 | |
| SCHEMBL11901898 | 0.73 | ALK (0.59) | ALKINSRROS1EGFRLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273077-B2 | Phosphorus derivatives as kinase inhibitors | ARIAD PHARMACEUTICALS, INC. (US) | 2016-03-01 | — | — | US | claimed |