Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250659 | 0.90 | NCOA1 (0.46) | NCOA1NCOA3PTGS2LMNABRD4 | |
| SCHEMBL17528777 | 0.88 | LTA4H (0.41) | LTA4HTSHRCA4LMNAGAA | |
| SCHEMBL17528781 | 0.84 | CA4 (0.43) | LTA4HCA4PTGS2LMNAGAA | |
| SCHEMBL13289 | 0.83 | LTA4H (0.50) | LTA4HTSHRCA4LMNAKMT2A | |
| SCHEMBL16415989 | 0.80 | LTA4H (0.47) | LTA4HTSHRCA4LMNAKMT2A | |
| SCHEMBL11681119 | 0.80 | LTA4H (0.47) | LTA4HTSHRCA4LMNAKMT2A | |
| Iodide SCHEMBL5553135 | 0.80 | LTA4H (0.47) | LTA4HTSHRCA4LMNAKMT2A | |
| SCHEMBL8113527 | 0.80 | LTA4H (0.47) | LTA4HTSHRCA4LMNAKMT2A | |
| SCHEMBL8662152 | 0.80 | LTA4H (0.47) | LTA4HTSHRCA4LMNAKMT2A | |
| SCHEMBL3009883 | 0.80 | LTA4H (0.47) | LTA4HTSHRCA4LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4190769-A1 | APPLICATION OF POLYDENTATE PHOSPHITE LIGAND IN CATALYTIC SYNTHESIS OF ADIPONITRILE | Zhejiang University (CN) | 2023-06-07 | — | — | EP | disclosed |
| WO-2023060929-A1 | APPLICATION OF POLYDENTATE PHOSPHITE LIGAND IN CATALYTIC SYNTHESIS OF ADIPONITRILE | 浙江大学 | 2023-04-20 | — | — | WO | disclosed |
| EP-2870167-B1 | STABLE LIGAND MIXTURES AND PROCESSES FOR MAKING SAME | INVISTA TEXTILES UK LTD (GB) | 2021-12-29 | — | — | EP | disclosed |
| US-11059835-B2 | Synthesis of cephalosporin compounds | MERCK SHARP & DOHME CORP. (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200385404-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2020-12-10 | — | — | US | disclosed |
| EP-3180347-B1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | MERCK SHARP & DOHME (US) | 2020-09-23 | — | — | EP | disclosed |
| US-10662202-B2 | Synthesis of cephalosporin compounds | MERCK SHARP & DOHM CORP. (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190263831-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-08-29 | — | — | US | disclosed |
| US-9834505-B2 | Stable ligand mixtures and processes for making same | INVISTA NORTH AMERICA S.A.R.L. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170275300-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275300-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2017-09-28 | — | — | US | disclosed |
| WO-2016025839-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2016-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662202-B2 | Synthesis of cephalosporin compounds | COASY, DDT, PEPD | LTA4H 4463/4885TSHR 3778/4885NCOA1 3929/4885 |
| US-20200385404-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | COASY, DDT, PEPD | LTA4H 4463/4885TSHR 3778/4885NCOA1 3929/4885 |
| US-11059835-B2 | Synthesis of cephalosporin compounds | COASY, DDT, PEPD | LTA4H 4463/4885TSHR 3778/4885NCOA1 3929/4885 |
| US-20170275300-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | COASY, NRDC, NUCB2 | LTA4H 4651/4885TSHR 3794/4885NCOA1 1883/4885 |
| US-20190263831-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | COASY, DDT, PEPD | LTA4H 4463/4885TSHR 3778/4885NCOA1 3929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.