Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 20/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.52 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529190 | 1.00 | PIK3CB (0.59) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL16308175 | 0.95 | PIK3CB (0.61) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL15029403 | 0.95 | PIK3CB (0.61) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL15029965 | 0.91 | PIK3CB (0.65) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL15009256 | 0.90 | PIK3CB (0.63) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL13248001 | 0.89 | PIK3CB (0.65) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL16308207 | 0.89 | PDCD1 (0.51) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL16308205 | 0.89 | PDCD1 (0.51) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL15030005 | 0.86 | PIK3CB (0.58) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL10124940 | 0.85 | PIK3CB (0.57) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604601-B1 | HETERO RING COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-02-24 | — | — | EP | disclosed |