Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 10/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529135 | 0.89 | PIK3CA (0.47) | PIK3CBPIK3CAPIK3CDNAPEPLDPIK3R1 | |
| SCHEMBL15029932 | 0.89 | NAPEPLD (0.46) | PIK3CBPIK3CAPIK3CDNAPEPLDPIK3R1 | |
| SCHEMBL16308154 | 0.88 | PIK3CB (0.41) | PIK3CBPIK3CAPIK3CDNAPEPLDPIK3R1 | |
| SCHEMBL17529088 | 0.87 | PIK3CB (0.40) | PIK3CBPIK3CAPIK3CDNAPEPLDPIK3R1 | |
| SCHEMBL17529203 | 0.84 | PIK3CA (0.41) | PIK3CBPIK3CAPIK3CDNAPEPLDPIK3R1 | |
| SCHEMBL15029959 | 0.82 | PIK3CB (0.46) | PIK3CBPIK3CAPIK3CDNAPEPLDPIK3R1 | |
| SCHEMBL15029918 | 0.81 | PIK3CB (0.45) | PIK3CBPIK3CAPIK3CDNAPEPLDPIK3R1 | |
| SCHEMBL17529049 | 0.80 | PDCD1 (0.39) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL10124320 | 0.78 | PIK3CB (0.51) | PIK3CBPIK3CAPIK3CDNAPEPLDPIK3R1 | |
| SCHEMBL15029823 | 0.77 | PIK3CB (0.57) | PIK3CBPIK3CAPIK3CDNAPEPLDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604601-B1 | HETERO RING COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-02-24 | — | — | EP | disclosed |