Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.59 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529032 | 0.85 | PIK3CB (0.47) | PIK3CAPIK3CBPIK3CDPIK3R1PIK3CG | |
| SCHEMBL15029985 | 0.83 | PIK3CA (0.56) | PIK3CAPIK3CBPIK3CDPIK3R1PIK3CG | |
| SCHEMBL15029618 | 0.83 | PIK3CB (0.65) | PIK3CAPIK3CBPIK3CDPIK3R1PIK3CG | |
| SCHEMBL15029345 | 0.83 | PIK3CB (0.67) | PIK3CAPIK3CBPIK3CDPIK3R1PIK3CG | |
| SCHEMBL17529050 | 0.82 | PIK3CB (0.51) | PIK3CAPIK3CBPIK3CDPIK3R1PIK3CG | |
| SCHEMBL17529135 | 0.81 | PIK3CA (0.47) | PIK3CAPIK3CBPIK3CDPIK3R1PIK3CG | |
| SCHEMBL17529053 | 0.80 | PIK3CB (0.48) | PIK3CAPIK3CBPIK3CDPIK3R1PIK3CG | |
| SCHEMBL16308161 | 0.80 | PIK3CA (0.50) | PIK3CAPIK3CBPIK3CDPIK3R1PIK3CG | |
| SCHEMBL2815524 | 0.80 | PIK3CA (0.75) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL17529031 | 0.79 | PIK3CB (0.60) | PIK3CAPIK3CBPIK3CDPIK3R1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604601-B1 | HETERO RING COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-02-24 | — | — | EP | disclosed |