Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529335 | 0.95 | TAAR1 (0.70) | TAAR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16681664 | 0.90 | ALOX15 (0.73) | TAAR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12176917 | 0.85 | MAPT (0.63) | TAAR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15997328 | 0.85 | MAPT (0.62) | TAAR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15997433 | 0.85 | MAPT (0.62) | TAAR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16420840 | 0.85 | MAPT (0.62) | TAAR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8200090 | 0.84 | TAAR1 (1.00) | TAAR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28711032 | 0.83 | ALOX15 (0.74) | MAPTALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL12297943 | 0.82 | KMT2A (1.00) | TAAR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17529373 | 0.82 | TAAR1 (0.53) | TAAR1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107082773-B | Sulfate of intestinal 2B type sodium phosphate cotransporter inhibitor and crystal form thereof | 江苏恒瑞医药股份有限公司 | 2020-07-28 | — | — | CN | disclosed |
| WO-2016026372-A1 | THIENOCYCLOALKYL OR THIENOHETEROCYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2016-02-25 | — | — | WO | disclosed |