SCHEMBL17529934

SCHEMBL17529934

OOC1Cc2ccc3ccccc3c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.40
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP2A6 P11509 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP1A2 P05177 3/20 0.38
CYP2C19 P33261 3/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2D6 P10635 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
KMT2A Q03164 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20465817 0.82 ANPEP (0.40) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL6986089 0.76 HSD17B10 (0.42) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL20469317 0.70 ALDH1A1 (0.33) ANPEPALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL19100030 0.70 ANPEP (0.39) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL1824058 0.70 ANPEP (0.39) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL9515388 0.69 ANPEP (0.41) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL9515024 0.69 ANPEP (0.41) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL9515081 0.69 ANPEP (0.41) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL9874592 0.69 ANPEP (0.41) ANPEPALDH1A1HSD17B10CYP2A6TSHR
Hydrochloric Acid SCHEMBL9516378 0.68 ANPEP (0.40) ANPEPALDH1A1CYP1A2CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3413370-B1 OXYGEN SUBSTITUTED BENZOCLOBUTENES DERIVED COMPOSITIONS FOR ELECTRONIC DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-25 EP disclosed
EP-3183760-B1 OXYGEN SUBSTITUTED BENZOCLOBUTENES DERIVED COMPOSITIONS FOR ELECTRONIC DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-25 EP disclosed
US-10297755-B2 Oxygen substituted benzoclobutenes derived compositions for electronic devices DOW GLOBAL TECHNOLOGIES LLC (US) 2019-05-21 US disclosed
US-10256410-B2 Compositions comprising oxygen substituted benzocyclobutenes and dienophiles, and electronic devices containing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-09 US disclosed
US-20170170398-A1 OXYGEN SUBSTITUTED BENZOCLOBUTENES DERIVED COMPOSITIONS FOR ELECTRONIC DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2017-06-15 US disclosed
US-20170170400-A1 COMPOSITIONS COMPRISING OXYGEN SUBSTITUTED BENZOCYCLOBUTENES AND DIENOPHILES, AND ELECTRONIC DEVICES CONTAINING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2017-06-15 US disclosed
WO-2016028906-A1 OXYGEN SUBSTITUTED BENZOCLOBUTENES DERIVED COMPOSITIONS FOR ELECTRONIC DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-25 WO disclosed
WO-2016026451-A1 COMPOSITIONS COMPRISING OXYGEN SUBSTITUTED BENZOCYCLOBUTENES AND DIENOPHILES, AND ELECTRONIC DEVICES CONTAINING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-25 WO disclosed
WO-2016026123-A1 COMPOSITIONS COMPRISING OXYGEN SUBSTITUTED BENZOCYCLOBUTENES AND DIENOPHILES, AND ELECTRONIC DEVICES CONTAINING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-25 WO disclosed