Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DVL1 | O14640 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798359 | 0.99 | SERPINE1 (0.53) | SERPINE1POLBALDH1A1KDM4ELMNA | |
| SCHEMBL1796188 | 0.92 | SERPINE1 (0.45) | SERPINE1POLBALDH1A1KDM4ELMNA | |
| SCHEMBL1796032 | 0.92 | SERPINE1 (0.45) | SERPINE1POLBALDH1A1KDM4ELMNA | |
| SCHEMBL1798357 | 0.83 | SERPINE1 (0.62) | SERPINE1POLBALDH1A1KDM4ELMNA | |
| SCHEMBL1796031 | 0.76 | SERPINE1 (0.53) | SERPINE1POLBALDH1A1KDM4ELMNA | |
| SCHEMBL1796187 | 0.76 | SERPINE1 (0.53) | SERPINE1POLBALDH1A1KDM4ELMNA | |
| SCHEMBL1798356 | 0.71 | SERPINE1 (0.71) | SERPINE1POLBALDH1A1KDM4EG6PD | |
| SCHEMBL1015522 | 0.71 | RAB9A (0.55) | SERPINE1POLBALDH1A1KDM4ELMNA | |
| SCHEMBL1014856 | 0.70 | SERPINE1 (0.51) | SERPINE1POLBALDH1A1KDM4ELMNA | |
| SCHEMBL1015397 | 0.70 | SERPINE1 (0.50) | SERPINE1POLBALDH1A1KDM4EG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990057-A1 | NOVEL USE FOR PAI-1 INHIBITOR | Renascience Co., Ltd. (JP) | 2016-03-02 | — | — | EP | disclosed |