Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530763 | 0.91 | KDM4E (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL17530825 | 0.84 | PRMT5 (0.38) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL716728 | 0.80 | PIK3CD (0.57) | TSHRL3MBTL1PIK3CDALOX15CASP1 | |
| SCHEMBL17530806 | 0.72 | KDM4E (0.36) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL714331 | 0.71 | PIK3CD (0.59) | KDM4EMEN1KMT2APIK3CDPIK3C2B | |
| SCHEMBL17530800 | 0.68 | IRAK4 (0.38) | MAPTKDM4ESMN1; SMN2LMNATSHR | |
| SCHEMBL715578 | 0.66 | PIK3CD (0.47) | PIK3CDPIK3C2B | |
| SCHEMBL14595394 | 0.63 | CHRM4 (0.58) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21171317 | 0.62 | OPRK1 (0.73) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12162012 | 0.60 | PRKDC (0.59) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |