Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 5/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530802 | 1.00 | SOS1 (0.42) | SOS1PIK3CDMAPTPOLBLMNA | |
| SCHEMBL715529 | 0.83 | MAPT (0.47) | PIK3CDMAPTPOLBLMNATSHR | |
| SCHEMBL715528 | 0.83 | MAPT (0.47) | PIK3CDMAPTPOLBLMNATSHR | |
| SCHEMBL716682 | 0.81 | MAPT (0.48) | SOS1MAPTPOLBLMNATSHR | |
| SCHEMBL15875835 | 0.79 | PIK3CD (0.44) | SOS1PIK3CDMAPTLMNAALDH1A1 | |
| SCHEMBL15875832 | 0.79 | PIK3CD (0.44) | SOS1PIK3CDMAPTLMNAALDH1A1 | |
| SCHEMBL716672 | 0.78 | PIK3CD (0.51) | PIK3CDMAPTTSHRALDH1A1KDM4E | |
| SCHEMBL721701 | 0.74 | KDR (0.41) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL721702 | 0.74 | KDR (0.41) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL714883 | 0.73 | MAPT (0.51) | MAPTPOLBLMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | disclosed |