Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 10/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530857 | 0.92 | IDH1 (0.34) | SOS1PIK3CDLRRK2IDH1OPRK1 | |
| SCHEMBL714121 | 0.84 | SOS1 (0.38) | SOS1PIK3CDLRRK2IDH1OPRK1 | |
| SCHEMBL714122 | 0.84 | SOS1 (0.38) | SOS1PIK3CDLRRK2IDH1OPRK1 | |
| SCHEMBL17530792 | 0.84 | IDH1 (0.44) | PIK3CDIDH1 | |
| SCHEMBL17530773 | 0.84 | SOS1 (0.34) | SOS1IDH1OPRK1 | |
| SCHEMBL15899927 | 0.81 | PIK3CD (0.41) | SOS1PIK3CDLRRK2OPRK1 | |
| SCHEMBL15899862 | 0.81 | PIK3CD (0.41) | SOS1PIK3CDLRRK2 | |
| SCHEMBL15327034 | 0.80 | TNF (0.38) | SOS1PIK3CD | |
| SCHEMBL721429 | 0.78 | IDH1 (0.36) | SOS1PIK3CDIDH1 | |
| SCHEMBL721428 | 0.78 | IDH1 (0.36) | SOS1PIK3CDIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |