Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17531092 | 0.88 | NPC1 (0.38) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL13074567 | 0.81 | NPC1 (0.43) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL255052 | 0.74 | NPC1 (0.61) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL1405393 | 0.74 | NPC1 (0.61) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11693056 | 0.74 | NPC1 (0.61) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL17446281 | 0.74 | NPC1 (0.61) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11693067 | 0.74 | NPC1 (0.61) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL14514356 | 0.71 | NPC1 (0.42) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL5301634 | 0.70 | NPC1 (0.48) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11844645 | 0.70 | NPC1 (0.48) | NPC1RAB9AMAPTL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9268065-B1 | Composition for polarizing film, polarizing film, and display device including the polarizing film | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-02-23 | — | — | US | disclosed |