Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16076753 | 0.79 | CA1 (0.32) | SLC7A5MEN1KMT2A | |
| SCHEMBL14450702 | 0.79 | CA1 (0.32) | SLC7A5MEN1KMT2A | |
| SCHEMBL30739107 | 0.79 | CA1 (0.32) | SLC7A5MEN1KMT2A | |
| SCHEMBL16556773 | 0.78 | SLC1A3 (0.32) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL755790 | 0.77 | ADAMTS4 (0.33) | SLC7A5SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1983612 | 0.77 | ADAMTS4 (0.33) | SLC7A5SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3294965 | 0.77 | SLC7A5 (0.36) | SLC7A5GABRR1SMN1; SMN2SLC1A3SLC1A2 | |
| SCHEMBL8220159 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL8223189 | 0.73 | CA14 (0.35) | CA12CA14SMN1; SMN2 | |
| SCHEMBL30888455 | 0.72 | SLC7A5 (0.43) | SLC7A5GABRR1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014082379-A9 | SPIRO RING COMPOUND AS HEPATITIS C VIRUS (HCV) INHIBITOR AND USES THEREOF FIELD OF THE INVENTION | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2016-02-25 | — | — | WO | disclosed |