SCHEMBL17533935

SCHEMBL17533935

Brc1ccc2c(c1)C1(c3ccccc3Cc3ccccc31)c1cc(Br)ccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.46
TRPA1 O75762 1/20 0.41
TDP2 O95551 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
METAP1 P53582 1/20 0.39
HTR2A P28223 3/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SLC6A2 P23975 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16879344 0.89 TDP1 (0.49) PDK2TRPA1TDP2TDP1L3MBTL1
SCHEMBL16878998 0.86 TDP1 (0.50) PDK2TRPA1TDP2TDP1L3MBTL1
SCHEMBL31613856 0.86 TDP1 (0.46) PDK2TRPA1TDP2TDP1L3MBTL1
SCHEMBL29399278 0.83 PDK2 (0.58) PDK2TDP2TDP1L3MBTL1CA1
SCHEMBL783450 0.83 PDK2 (0.58) PDK2TDP2TDP1L3MBTL1CA1
SCHEMBL29397249 0.83 PDK2 (0.58) PDK2TDP2TDP1L3MBTL1CA1
SCHEMBL29574412 0.83 PDK2 (0.58) PDK2TDP2TDP1L3MBTL1CA1
SCHEMBL996751 0.83 PDK2 (0.58) PDK2TDP2TDP1L3MBTL1CA1
SCHEMBL783463 0.83 PDK2 (0.58) PDK2TDP2TDP1L3MBTL1CA1
SCHEMBL29530902 0.83 PDK2 (0.58) PDK2TDP2TDP1L3MBTL1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172775-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-04-20 EP disclosed
US-9691989-B2 Carbo- and heterocyclic spiro compounds as donor materials for organic photovoltaics and their preparation THE UNIVERSITY OF HONG KONG (CN) 2017-06-27 US disclosed
US-9691989-B2 Carbo- and heterocyclic spiro compounds as donor materials for organic photovoltaics and their preparation THE UNIVERSITY OF HONG KONG (CN) 2017-06-27 US disclosed
WO-2016023458-A1 NOVEL CARBO- AND HETEROCYCLIC SPIRO COMPOUNDS AS DONOR MATERIALS FOR ORGANIC PHOTOVOLTAICS AND THEIR PREPARATION THE UNIVERSITY OF HONG KONG (CN) 2016-02-18 WO disclosed